| List of contributors | page ix | |
| Foreword | xiii | |
| Preface | xv | |
| 1 | The cannabinoid system: from the point of view of a chemist | 1 |
| Raphael Mechoulam and Lumir Hanuš | ||
| 2 | How cannabis works in the brain | 19 |
| Leslie Iversen | ||
| 3 | Acute and subacute psychomimetic effects of cannabis in humans | 41 |
| David J. Castle and Nadia Solowij | ||
| 4 | The association between cannabis use and depression: a review of the evidence | 54 |
| Louisa Degenhardt, Wayne Hall, Michael Lynskey, Carolyn Coffey and George Patton | ||
| 5 | Cannabis and psychosis proneness | 75 |
| Hélène Verdoux | ||
| 6 | Is there a specific ‘cannabis psychosis’? | 89 |
| Wayne Hall and Louisa Degenhardt | ||
| 7 | Cannabis as a potential causal factor in schizophrenia | 101 |
| Louise Arseneault, Mary Cannon, John Witton and Robin Murray | ||
| 8 | Cannabis abuse and the course of schizophrenia | 119 |
| Don Linszen, Bart Peters and Lieuwe de Haan | ||
| 9 | The endogenous cannabinoid system in schizophrenia | 127 |
| Suresh Sundram, Brian Dean and David Copolov | ||
| 10 | Cannabinoid ‘model’ psychosis, dopamine–cannabinoid interactions and implications for schizophrenia | 142 |
| D. Cyril D’Souza, Hyun-Sang Cho, Edward B. Perry and John H. Krystal | ||
| 11 | Motives that maintain cannabis use among individuals with psychotic disorders | 166 |
| Catherine Spencer | ||
| 12 | Addressing cannabis abuse in people with psychosis | 186 |
| Wynne James and David J. Castle | ||
| 13 | Residual cognitive effects of long-term cannabis use | 198 |
| Harrison G. Pope, Jr and Deborah Yurgelun-Todd | ||
| Index | 211 |